Adult downs syndrome
As they age, those affected by Down syndrome have a greatly increased risk of developing a type of dementia that's either the same as or very similar to Alzheimer's disease. Down syndrome — also known as trisomy 21 — is a condition in which a person is born with extra genetic material from chromosome 21, one of the 23 human chromosomes. Most people with Down syndrome have a full extra copy of chromosome 21, and so they have three copies instead of the usual two. Scientists think the extra copy results from a random error in the specialized cell division that produces eggs and sperm. Researchers have so far identified more than genes on chromosome 21, and they expect to find more.
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Down syndrome is a genetic condition that causes delays in physical and intellectual development. Individuals with Down syndrome have 47 chromosomes instead of the usual It is the most frequently occurring chromosomal disorder. Down syndrome is not related to race, nationality, religion or socioeconomic status.
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There are many misconceptions about people with Down syndrome. These misconceptions are largely a result of two contributing factors: 1 the syndrome itself has changed so fundamentally for the better with the dismantling of the inhumane institutions where people with Down syndrome were previously forced to live, and. The Global Down Syndrome Foundation GLOBAL is dedicated to correcting misconceptions and over time providing funding for research that will better address medical and cognitive issues associated with the condition. The CDC research shows that the chances of having a baby with Down syndrome does increase with age.
Despite the unique clinical comorbidities among adults with Down syndrome, there are no clinical guidelines for the care of these patients. Using the GRADE Grading of Recommendations, Assessment, Development, and Evaluation methodology and the Evidence-to-Decision framework, in January , the member Workgroup and 16 additional clinical and scientific experts, nurses, patient representatives, and a methodologist developed clinical recommendations. A statement of good practice was made when there was a high level of certainty that the recommendation would do more good than harm, but there was little direct evidence. An updated search identified 2 additional studies, for a total of 22 included studies 3 systematic reviews, 19 primary studies , which were reviewed and synthesized.